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MANUAL OF ENVIRONMENTAL MICROBIOLOGY, 3RD EDITION. Authors: Christon J. Hurst; Ronald L. Crawford; Jay L. Garland; David A. Lispon; Aaron L. Mills 

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Arsenic's toxicity comes from the affinity of arsenic(III) oxides for thiols. Thiols, in the form of cysteine residues and cofactors such as lipoic acid and coenzyme A, are situated at the active sites of many important enzymes.

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